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AP50 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 27355-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16885585

  • 1236.20 SEK / 20µL
Estimated Shipment: 07-12-2021

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Description

Description

The heterotetrameric coat assembly protein complex, also known as the adaptor-related protein complex 2 (AP-2), belongs to the adaptor complexes medium subunits family. The mu 1 subunit of the AP-2 complex (AP2M1) is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. AP2M1 has also been shown to associate with the HIV-1 protein Nef, suggesting that Nef may use AP-2 complex to enhance the rate of endocytosis of both CD4 and class I MHC. AP2M1 may also play an important role in regulating the intracellular trafficking and function of cytotoxic T-lymphocyte associated (CTLA)-4 protein. At least two isoforms of AP2M1 are known to exist.
Specifications

Specifications

AP50
0.23 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P84091, P84092, Q96CW1
Adaptin mu2, AP 2 complex subunit mu, AP 2 mu chain, AP2M1, AP50, CLAPM1, HA2 50 kDa subunit, KIAA0109, mu2
Rabbit
IgG
20 μL
-20°C
Primary
116563, 1173, 11773
Western Blot, Immunohistochemistry (Paraffin)
Unconjugated
AP2M1
Liquid
Ap2m1
AP50 Fusion Protein Ag26059
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Rat, Mouse
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