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APP (Amyloid Precursor Protein) Mouse anti-Human, Mouse, Rat, Clone: 22C11, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-9749-80

Additional Details : Weight : 0.09500kg

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Product Code. 15567626

  • 1214.00 SEK / 25µg


Estimated Shipment
15-12-2020
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Description

Description

Applications Tested: This 22C11 antibody has been tested by immunocytochemistry of methanol-fixed cells and can be used at less than or equal to 2.5 µg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered. Amyloid Precursor Protein (APP) or Amyloid beta protein functions as a cell surface kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1; APP is rapidly internalized via clathrin-coated pits. APP is important for neurite growth, neuronal adhesion and axonogenesis. Mutations in the APP gene can lead to Alzheimer disease 1 (AD1). This anitbody recognizes APP (b-APP770) with a MW of approximately 100kDa.
Specifications

Specifications

APP (Amyloid Precursor Protein)
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P05067, P12023, P08592
AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN2
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry
22C11
Unconjugated
APP
Liquid
APP
IgG1, kappa
25 μg
4° C
Primary
11820, 351, 54226
Videos
SDS
Documents

For Research Use Only.