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ARPC3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 14652-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16823404

  • 1236.20 SEK / 20µL
Estimated Shipment: 07-12-2021

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Description

Description

The maf oncogene was identified by structural analysis of the AS42 avian transforming retrovirus genome. The Maf family is divided into two subclasses, large Mafs (vMaf, cMaf, MafB and Nrl) and small Mafs (MafF, MafK, and MafG). Both subclasses contain leucinezipper motifs, which allow homodimerization as well as heterodimerization with a variety of other bZip transcription factors. Large Mafs also contain an acidic transactivation domain absent in the small Maf proteins. Although they do not possess inherent transactivation activity, small Maf proteins can act as positive regulators of transcription by targeting transcriptionally active dimerization partners to specific DNA regulatory elements. Conversely, small Mafs can act also as negative regulators of transcription by recruiting transcriptional repressors or by forming homodimers that can replace active dimers. Human MafF was isolated in a yeast one-hybrid system from a human myometrium cDNA library. Human MAFF encodes a 164 amino acids proten. Like other small MAFF proteins, it contains an extended leucine zipper structure and lacks an N-terminal transactivating domain. The three small Maf proteins have been implicated in a number of physiological processes, including development, differentiation, haematopoiesis and stress response. Interestingly, these three proteins regulate the stress response via different mechanisms.
Specifications

Specifications

ARPC3
0.48 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O15145, Q9JM76
ARC21, Arp2/3 complex 21 kDa subunit, ARPC3, p21 Arc
Rabbit
IgG
20 μL
-20°C
Primary
10094, 288669, 56378
Western Blot
Unconjugated
ARPC3
Liquid
Arpc3
ARPC3 Fusion Protein Ag6249
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Mouse, Human, Rat
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