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AS601245, MedChemExpress

Produktkod. 16497067
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Produktkod. 16497067 Leverantör Medchem Express Leverantörsnummer HY11010

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Beskrivning

MedChemExpress AS601245 is an orally active, selective, ATP competitive JNK (c-Jun NH2-terminal protein kinase) inhibitor with IC50s of 150, 220, and 70 nM for three JNK human isoforms (hJNK1, hJNK2, and hJNK3), respectively. AS601245 exhibits 10- to 20-fold selectivity over c-src, CDK2, and c-Raf and more than 50- to 100-fold selectivity over a range of Ser/Thr- and Tyr-protein kinases. Neuroprotective properties.

AS601245 is an orally active, selective, ATP competitive JNK (c-Jun NH2-terminal protein kinase) inhibitor with IC50s of 150, 220, and 70 nM for three JNK human isoforms (hJNK1, hJNK2, and hJNK3), respectively. AS601245 exhibits 10- to 20-fold selectivity over c-src, CDK2, and c-Raf and more than 50- to 100-fold selectivity over a range of Ser/Thr- and Tyr-protein kinases. Neuroprotective properties.

Specifikationer

Kemiskt namn eller material AS601245
Fysisk form Solid
CAS 345987-15-7
Färg Yellow
Kvantitet 5 mg
Anteckningar om renhetsgrad Research
Molekylformel C20H16N6S
För användning med (applikation) Cancer-Kinase/protease
Löslighetsinformation DMSO : 10 mg/mL (26.85 mM; Need ultrasonic)
LEDER N#CC(C1=CC=NC(NCCC2=CC=CN=C2)=N1)C3=NC4=CC=CC=C4S3
Molekylvikt (g/mol) 372.45
Formel vikt 372.45
Procent renhet 98.7%
Kvalitet Research
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