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ATF2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 14834-1-AP-20UL
Additional Details : Weight : 0.00010kg
Description
This antibody is a rabbit polyclonal antibody raised against a peptide mapping within human ATF2. The calculated molecular weight of ATF2 is 55 kDa, but the modified ATF2 protein is about 70 kDa.
The transcription factor ATF-2 (also called CRE-BP1) binds to both AP-1 and CRE DNA response elements and is a member of the ATF/CREB family of leucine zipper proteins. ATF-2 interacts with a variety of viral oncoproteins and cellular tumor suppressors and is a target of the SAPK/JNK and p38 MAP kinase signaling pathways. Various forms of cellular stress, including genotoxic agents, inflammatory cytokines and UV irradiation, stimulate the transcriptional activity of ATF-2. Cellular stress activates ATF-2 by phosphorylation of Thr69 and Thr71. Both SAPK and p38 MAPK have been shown to phosphorylate ATF-2 at these sites in vitro and in cells transfected with ATF-2.Specifications
ATF2 | |
Polyclonal | |
Unconjugated | |
ATF2 | |
ATF2, CRE BP1, CREB 2, CREB2, CREBP1, HB16, TREB7 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
11909, 1386, 81647 | |
-20°C | |
Liquid |
Western Blot, Immunohistochemistry (Paraffin) | |
0.13 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
P15336, P16951, Q00969 | |
Atf2 | |
Peptide | |
20 μL | |
Primary | |
Rat, Mouse, Human | |
Antibody | |
IgG |