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ATF2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

1656.73 SEK - 4721.67 SEK

Specifications

Antigen ATF2
Concentration 0.13 mg/mL
Applications Western Blot, Immunohistochemistry (Paraffin)
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16823694
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Proteintech
14834-1-AP-20UL
20 μL
1656.73 SEK
20µL
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Estimated Shipment: 14-05-2024
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16813694
View Documents Promotion Details
Proteintech
14834-1-AP-150UL
150 μL
4721.67 SEK
150µL
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Estimated Shipment: 14-05-2024
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Description

Description

This antibody is a rabbit polyclonal antibody raised against a peptide mapping within human ATF2. The calculated molecular weight of ATF2 is 55 kDa, but the modified ATF2 protein is about 70 kDa.

The transcription factor ATF-2 (also called CRE-BP1) binds to both AP-1 and CRE DNA response elements and is a member of the ATF/CREB family of leucine zipper proteins. ATF-2 interacts with a variety of viral oncoproteins and cellular tumor suppressors and is a target of the SAPK/JNK and p38 MAP kinase signaling pathways. Various forms of cellular stress, including genotoxic agents, inflammatory cytokines and UV irradiation, stimulate the transcriptional activity of ATF-2. Cellular stress activates ATF-2 by phosphorylation of Thr69 and Thr71. Both SAPK and p38 MAPK have been shown to phosphorylate ATF-2 at these sites in vitro and in cells transfected with ATF-2.
Specifications

Specifications

ATF2
Western Blot, Immunohistochemistry (Paraffin)
Unconjugated
Rabbit
Rat, Mouse, Human
P15336, P16951, Q00969
11909, 1386, 81647
Peptide
Primary
-20°C
ATF2
0.13 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
ATF2, CRE BP1, CREB 2, CREB2, CREBP1, HB16, TREB7
Atf2
IgG
Antigen Affinity Chromatography
Antibody
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SDS
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