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ATG16L1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 19812-1-AP-20UL
Additional Details : Weight : 0.00010kg
Description
Autophagy related protein 16 L is encoded by the ATG16L gene and is located on chromosome 2 in humans. It is also known as WD30 or IBD10 (Inflammatory Bowel Disease 10). ATG 12 and ATG5 conjugate with each other and undergoes homo oligomerisation with ATG16L to form an 800 kDa complex called the Atg16L complex. This complex facilitates coupling or lipidation of LC3 to phosphatidylethanolamine (PE) and this ubiquitin-like conjugation system is a widely used marker for autophagy. However, the ATG 16L complex along with other ATGs like ATG 18 and ATG 21 prevent the premature cleavage of ATG8-PE by the cysteine protease, Atg4 until the autophagosome is deemed complete.Specifications
ATG16L1 | |
Polyclonal | |
Unconjugated | |
ATG16L1 | |
APG16 like 1, APG16L, ATG16L, ATG16L1, Autophagy related protein 16 1, IBD10, WDR30 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
55054, 77040 | |
-20°C | |
Liquid |
Western Blot, Immunoprecipitation | |
0.23 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
Q676U5, Q8C0J2 | |
ATG16L1 | |
ATG16L1 Fusion Protein Ag13844 | |
20 μL | |
Primary | |
Human, Mouse | |
Antibody | |
IgG |