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ATGL Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

1656.73 SEK - 4721.67 SEK

Specifications

Antigen ATGL
Concentration 0.41 mg/mL
Applications Immunocytochemistry, Western Blot, Immunofluorescence, Immunoprecipitation
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16886675
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Proteintech
55190-1-AP-20UL
20 μL
1656.73 SEK
20µL
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Estimated Shipment: 22-04-2024
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16876675
View Documents Promotion Details
Proteintech
55190-1-AP-150UL
150 μL
4721.67 SEK
150µL
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Estimated Shipment: 22-04-2024
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Description

Description

This antibody is specific to ATGL.

Lipolytic enzymes are required for mobilization of fatty acids from triglyceride stores in adipose tissue. Energy homeostasis is affected by dysfunctional lipolysis and may contribute to the pathogenesis of obesity and insulin resistance. Until recently, hormone-sensitive lipase (HSL) was the only enzyme known to hydrolyze triglycerides in mammalian adipose tissue. It is now thought that a second enzyme, adipose triglyceride lipase (ATGL), catalyzes the initial step in triglyceride hydrolysis. ATGL is highly expressed in adipose tissue of mice and humans. It exhibits high substrate specificity for triacylglycerol and is associated with lipid droplets. Inhibition of ATGL markedly decreases total adipose acyl-hydrolase activity. Thus, ATGL and HSL coordinately catabolize stored triglycerides in adipose tissue of mammals.
Specifications

Specifications

ATGL
Immunocytochemistry, Western Blot, Immunofluorescence, Immunoprecipitation
Unconjugated
Rabbit
Mouse, Rat, Human
P0C548, Q8BJ56, Q96AD5
361676, 57104, 66853
Peptide
Primary
-20°C
PNPLA2
0.41 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
1110001C14Rik, Adipose Triglyceride Lipase, ATGL, DESNUTRIN, FP17548, IPLA2 zeta, PEDF R, PNPLA2, Transport secretion protein 2, TTS 2.2, TTS2, TTS2.2
Pnpla2
IgG
Antigen Affinity Chromatography
Antibody
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