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AX-024 hydrochloride, MedChemExpress

Produktkod. 16492956
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16492956 25 mg
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Produktkod. 16492956 Leverantör Medchem Express Leverantörsnummer HY107390A

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MedChemExpress AX-024 hydrochloride is an orally available, first-in-class inhibitor of the TCR-Nck interaction that selectively inhibits TCR-triggered T cell activation with an IC50 ∼1 nM. AX-024 hydrochloride modulates cell signaling by targeting SH3 domains. AX-024 hydrochloride has low-acute toxicity and high potency and selectivity, and strongly inhibit the production of IL-6, TNF-α, IFN-γ, IL-10 and IL-17A.

AX-024 hydrochloride is an orally available, first-in-class inhibitor of the TCR-Nck interaction that selectively inhibits TCR-triggered T cell activation with an IC50 ∼1 nM. AX-024 hydrochloride modulates cell signaling by targeting SH3 domains. AX-024 hydrochloride has low-acute toxicity and high potency and selectivity, and strongly inhibit the production of IL-6, TNF-α, IFN-γ, IL-10 and IL-17A.

Specifikationer

Kemiskt namn eller material AX-024 hydrochloride
CAS 1704801-24-0
Färg White
Anteckningar om renhetsgrad Research
Molekylformel C21H23ClFNO2
Kvantitet 25 mg
Löslighetsinformation DMSO : 33 mg/mL (87.80 mM; Need ultrasonic and warming) ∣H2O : 16.67 mg/mL (44.35 mM; Need ultrasonic)
LEDER COC1=CC=C(OC2)C(C(C3=CC=C(F)C=C3)=C2CN4CCCC4)=C1.[H]Cl
Molekylvikt (g/mol) 375.86
Formel vikt 375.86
Procent renhet 99.12%
Kvalitet Research
Fysisk form Solid
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