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AX-024, MedChemExpress

Produktkod. 16482956
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16482956 25 mg
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16406827 5 mg
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16404128 10 mg
16400126 2 mg
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Produktkod. 16482956 Leverantör Medchem Express Leverantörsnummer HY107390

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MedChemExpress AX-024 is an orally available, first-in-class inhibitor of the TCR-Nck interaction that selectively inhibits TCR-triggered T cell activation with an IC50 ∼1 nM. AX-024 modulates cell signaling by targeting SH3 domains. AX-024 has low-acute toxicity and high potency and selectivity, and strongly inhibit the production of IL-6, TNF-α, IFN-γ, IL-10 and IL-17A.

AX-024 is an orally available, first-in-class inhibitor of the TCR-Nck interaction that selectively inhibits TCR-triggered T cell activation with an IC50 ∼1 nM. AX-024 modulates cell signaling by targeting SH3 domains. AX-024 has low-acute toxicity and high potency and selectivity, and strongly inhibit the production of IL-6, TNF-α, IFN-γ, IL-10 and IL-17A.

Specifikationer

Kemiskt namn eller material AX-024
CAS 1370544-73-2
Färg Light Yellow
Anteckningar om renhetsgrad Research
Molekylformel C21H22FNO2
Kvantitet 25 mg
Löslighetsinformation Ethanol : 100 mg/mL (294.64 mM; Need ultrasonic) ∣DMSO : 35 mg/mL (103.12 mM; Need ultrasonic and warming)
LEDER COC1=CC=C(OC2)C(C(C3=CC=C(F)C=C3)=C2CN4CCCC4)=C1
Molekylvikt (g/mol) 339.4
Formel vikt 339.4
Procent renhet 98.0%
Kvalitet Research
Fysisk form Powder
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Research purposes only

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