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Azithromycin dihydrate, Thermo Scientific™
Azithromycin dihydrate, CAS # 117772-70-0, is an azalide derived from erythromycin that shows antibacterial activity.
Brand: Thermo Scientific Alfa Aesar J66740.06
2991.18 SEK valid until 2026-07-03
BÄSTA PRIS på kampanj! Använd kampanjkod: "27965" för att få ditt kampanjpris.
| Kvantitet | 5g |
|---|
Produktkod. 15498209
-
4273.12 SEK
3835.65 SEK / 5g
Save 437.47 SEK
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Beskrivning
This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.
General Description
• Azithromycin dihydrate is the dihydrate form of azithromycin, an azalide derived from erythromycin, that shows antibacterial activity
• Azithromycin dihydrate reversibly binds to the 23S rRNA of the 50S ribosomal subunit of the bacterial ribosome of susceptible microorganisms, inhibiting the translocation step of protein synthesis by preventing the assembly of the 50S ribosomal subunit. This inhibits bacterial protein synthesis and cell growth, causing cell death
Application
• Azithromycin dihydrate shows anti-immunomodulatory and anti-inflammatory activities
• It shows antimalarial activity against Plasmodium falciparum and P. vivax, which are multidrug-resistant species
• In the laboratory, azithromycin dihydrate has been used in blocking buffer for indirect immunofluorescence
• It has been used in U87 cells for cell viability assay and flow cytometry analysis to study the Zika virus infection in glial cells
• Azithromycin dihydrate has been used in experiments to compare its antibacterial activity with PYRRO-C3D against Streptococcus pneumoniae biofilms
Specifikationer
| Azithromycin dihydrate | |
| White | |
| >110°C (230°F) | |
| C38H76N2O14 | |
| 717°C | |
| Soluble in DMSO at 20mg/mL; Also soluble in chloroform or ethylene chloride | |
| CCC1C(C(C(N(CC(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)O)C)C)C)O)(C)O.O.O | |
| 785.026 | |
| 785.01 |
| 117772-70-0 | |
| 5g | |
| Air sensitive | |
| MFCD01862248 | |
| N-Methyl-11-aza-10-deoxo-10-dihydroerythromycin A; CP-62993 | |
| SRMPHJKQVUDLQE-GTCGPNQGSA-N | |
| (2R,3S,4S,5R,8R,10R,11R,12S,13R,14R)-11-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-o | |
| 131845180 | |
| 98% |
Säkerhet och hantering
Produktbeteckning
Signalord
Riskkategorier
Faroangivelser
Skyddsangivelse
Kompletterande information
- Azithromycin dihydrate
Signalord
- Fara
Riskkategorier
- Luftvägssensibilisering Kategorija 1
- Preobcutljivost koze Kategorija 1
Faroangivelser
- H317-Kan orsaka allergisk hudreaktion.
- H334-Kan orsaka allergi- eller astmasymtom eller andningssvårigheter vid inandning.
Skyddsangivelse
- P280-Använd skyddshandskar/skyddskläder/ögonskydd/ansiktsskydd.
- P284-[Vid otillräcklig ventilation], använd andningsskydd.
- P302+P352-VID HUDKONTAKT: Tvätta med mycket vatten/.
- P304+P340-VID INANDNING: Flytta personen till frisk luft och se till att andningen underlättas.
- P333+P313-Vid hudirritation eller utslag: Sök läkarhjälp.
- P342+P311-Vid besvär i luftvägarna: Kontakta GIFTINFORMATIONSCENTRALEN/läkare/ .
- P362+P364-Ta av nedstänkta kläder och tvätta dem innan de används igen.
Kompletterande information
- MIXTURE LIST-Contain: Azithromycin hydrate
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