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  7. BAY 61-3606 dihydrochloride, MedChemExpress

BAY 61-3606 dihydrochloride, MedChemExpress

Produktkod. 16476278
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16476278 10 mg -
16438867 5 mg -
16422407 50 mg 50mg
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Produktkod. 16476278 Leverantör Medchem Express Leverantörsnummer HY14985

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Beskrivning

MedChemExpress BAY 61-3606 dihydrochloride is an orally available, ATP-competitive, reversible and highly selective Syk inhibitor with a Ki of 7.5 nM an IC50 of 10 nM.

BAY 61-3606 dihydrochloride reduces ERK1/2 and Akt phosphorylation in neuroblastoma cell. BAY 61-3606 dihydrochloride induces a large decrease of Syk phosphorylation in K-rn cell lysates. Bay 61-3606 dihydrochloride sensitizes TRAIL-induced apoptosis by downregulating Mcl-1 in breast cancer cells.

Specifikationer

Kemiskt namn eller material BAY 61-3606 dihydrochloride
CAS 648903-57-5
Färg Light Yellow
Anteckningar om renhetsgrad Research
Molekylformel C20H20Cl2N6O3
Kvantitet 10 mg
Löslighetsinformation H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
LEDER O=C(N)C1=CC=CN=C1NC2=NC(C3=CC=C(C(OC)=C3)OC)=CC4=NC=CN24.[H]Cl.[H]Cl
Molekylvikt (g/mol) 463.32
Formel vikt 463.32
Procent renhet 98.21%
Kvalitet Research
Fysisk form Solid
För användning med (applikation) COVID-19-immunoregulation
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Research purposes only

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