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BCR Mouse anti-Human, Clone:1E11G12, Abnova™

Produktkod. 16085216
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Kvantitet:
100 μg
Förpackningsstorlek:
100µg
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16085216 100 μg 100µg
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Produktkod. 16085216 Leverantör Abnova Leverantörsnummer MAB17933.100ug

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Beskrivning

Mouse monoclonal antibody raised against partial recombinant human BCR.

A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Specifikationer

Antigen BCR
Användningsområden ELISA, Flow Cytometry, Western Blot
Klassificering Monoclonal
Klona 1E11G12
Konjugera Unconjugated
Beskrivning breakpoint cluster region
Utspädning ELISA (1:10000)
Flow Cytometry (1:200-1:400)
Western Blot (1:100-1:500)
The optimal working dilution should be determined by the end user.
Formulering In PBS (0.05% sodium azide)
Gen BCR
Gene Alias ALL, BCR-ABL1, BCR1, CML, D22S11, D22S662, FLJ16453, PHL
Värd art Mouse
Immunogen Recombinant protein corresponding to amino acids 139-280 of human BCR.
Kvantitet 100 μg
Gen-ID (Entrez) 613
Målarter Human
Innehåll och lagring Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Produkttyp Antibody
Form Liquid
Isotyp IgG1
Visa mer Visa mindre
Produkttitel
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