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Tocris Bioscience™ Bexarotene
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Product Code. 18731348
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50 mg
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18731348 10 mg
18768788 50 mg
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Product Code. 18731348 Supplier Tocris Bioscience™ Supplier No. 5819/10

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Description

Potent and selective RXR agonist

Bexarotene is a potent and selective RXR agonist (EC50 values are 24, 25 and 33 nM for RXRβ, RXRγ and RXRα, respectively). Exhibits >300-fold selectivity for RXR over RAR receptors. Inhibits tumor cell invasion and migration in vitro, and inhibits metastasis and angiogenesis in mouse models. Also promotes brown adipogenic differentiation and induces brown adipogenic reprogramming from myoblasts.
TRUSTED_SUSTAINABILITY

Specifications

Kemiskt namn eller material 4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic acid
CAS 153559-49-0
Synonym LGD 1069
Kvantitet 10 mg
Mål Retinoid X Receptor Agonists
Molekylformel C24H28O2
Formel vikt 348.48
Renhet >99%
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