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Bexarotene, 98%, Thermo Scientific Chemicals

Produktkod. 15485879
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100 mg
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15485879 100 mg
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Produktkod. 15485879 Leverantör Thermo Scientific Alfa Aesar Leverantörsnummer J63701.MC
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Beskrivning

Synthetic retinoid analog with specific affinity for the retinoid X receptor

Bexarotene is used as a Synthetic retinoid analog with specific affinity for the retinoid X receptor, an antineoplastic agent, already approved as an oral antineoplastic agent for cutaneous T cell lymphoma and being investigated against other cancers. A study has found that bexarotene in a mouse Alzheimer's model lowered the most toxic form of β-amyloid peptide and increased cognitive ability.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Bexarotene is used as a Synthetic retinoid analog with specific affinity for the retinoid X receptor, an antineoplastic agent, already approved as an oral antineoplastic agent for cutaneous T cell lymphoma and being investigated against other cancers. A study has found that bexarotene in a mouse Alzheimer′s model lowered the most toxic form of β-amyloid peptide and increased cognitive ability.

Solubility
Soluble in DMSO and ethanol

Notes
Store in cool, dry conditions in well sealed containers. Keep container tightly closed.
TRUSTED_SUSTAINABILITY

Kemiska identifierare

CAS 153559-49-0
Molekylformel C24H28O2
Molekylvikt (g/mol) 348.49
MDL-nummer MFCD00932428
InChI-nyckel NAVMQTYZDKMPEU-UHFFFAOYSA-N
Synonym bexarotene, targretin, targrexin, targretyn, targret, bexarotenum, bexarotene usan, bexaroteno, bexaroten, targretin-gel
PubChem CID 82146
ChEBI CHEBI:50859
IUPAC-namn 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethenyl]benzoic acid
LEDER CC1=CC2=C(C=C1C(=C)C1=CC=C(C=C1)C(O)=O)C(C)(C)CCC2(C)C

Specifikationer

Kemiskt namn eller material Bexarotene
Smältpunkt 220°C to 225°C
Färg White
Kvantitet 100 mg
Merck Index 14,1194
Löslighetsinformation Soluble in DMSO and ethanol
Formel vikt 348.48
Procent renhet ≥99%
Fysisk form Powder

RUO – Research Use Only

Produkttitel
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