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Invitrogen™ BFSP2 Polyclonal Antibody

Beskrivning
Immunogen sequence: YVGTAPSGCI GGLGARVTRR ALGISSVFLQ GLRSSGLATV PAPGLERDHG AVEDLGGCLV EYMAKVHALE QVSQELETQL Highest antigen sequence indentity to the following orthologs: Rat - 89%, Mouse - 91%.
More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, the protein product of this gene (phakinin), and filensin, are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF). Mutations in this gene have been associated with juvenile-onset, progressive cataracts and Dowling-Meara epidermolysis bullosa simplex.
Specifikationer
Specifikationer
| Antigen | BFSP2 |
| Användningsområden | Immunohistochemistry (Paraffin) |
| Klassificering | Polyclonal |
| Koncentration | 0.05 mg/mL |
| Konjugera | Unconjugated |
| Formulering | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gen | BFSP2 |
| Genaccessionsnr. | Q13515 |
| Gene Alias | 49 kDa cytoskeletal protein; AI448593; beaded filament protein CP49; beaded filament structural protein 2; beaded filament structural protein 2, phakinin; bfps2, Cytoskeletal protein, 49-kD; BFSP2; CP 47; CP47; CP49; CTRCT12; DKEYP-73D8.2; hypothetical protein LOC494090; lens fiber cell beaded filament protein CP 47; Lens fiber cell beaded filament protein CP 49; lens intermediate filament-like light; LIFL-L; MGC142078; MGC142080; phakinin; PHAKOSIN; zgc:103750 |
| Gensymboler | BFSP2 |
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Produkttitel
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