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BIN1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 14647-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16813394

  • 4721.67 SEK / 150µL
Estimated Shipment: 02-04-2024
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Description

Description

This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in ten transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.
Specifications

Specifications

BIN1
Polyclonal
Unconjugated
BIN1
AMPH2, Amphiphysin II, Amphiphysin like protein, AMPHL, BIN1, bridging integrator 1, SH3P9
Rabbit
Antigen Affinity Chromatography
RUO
117028, 274, 30948
-20°C
Liquid
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
0.44 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O00499, O08539, O08839
Bin1
BIN1 Fusion Protein Ag6240
150 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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