Learn More
ACROBiosystems Biotinylated Human CD14 Protein, His, Avitag
4673.08 SEK - 20561.57 SEK
Specifications
Accession Number | AAH10507.1 |
---|---|
Molecular Weight (g/mol) | 38.6 kDa |
Source | Biotinylated Human CD14, His,Avitag (CD4-H8228) is expressed from human 293 cells (HEK293). It contains AA Thr 20 - Met 344 (Accession # P08571-1). |
Immunogen | Thr 20 - Met 344 |
Storage Requirements | -20°C |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
17206110
|
ACROBiosystems
CD4-H8228-200UG |
200 μg |
20561.57 SEK
200µg |
Estimated Shipment: 30-04-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
17216110
|
ACROBiosystems
CD4-H8228-25UG |
25 μg |
4673.08 SEK
25µg |
Estimated Shipment: 30-04-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
Cluster of differentiation 14 (CD14), is a cell surface glycoprotein, and is a is a component of the innate immune system. CD14 is a myelomonocytic differentiation antigen preferentially expressed on monocytes, macrophages, and activated granulocytes. CD14 exists in two forms. Either it is anchored into the membrane by a glycosylphosphatidylinositol tail (mCD14) or it appears in a soluble form (sCD14). Soluble CD14 either appears after shedding of mCD14 (48 kDa) or is directly secreted from intracellular vesicles (56 kDa). CD14 acts as a co-receptor (along with the Toll-like receptor TLR 4 and MD-2) for the detection of bacterial lipopolysaccharide (LPS). CD14 can bind LPS only in the presence of lipopolysaccharide-binding protein (LBP). CD14 has been proposed to be involved in various biological processes, including transportation of other lipids, cell-cell interaction during different immune responses, as well as recognition of apoptotic cells. Although LPS is considered its main ligand, CD14 also recognizes other pathogen-associated molecular patterns. CD14+ cells are monocytes that can differentiate into a host of different cells. CD14 has been shown to interact with Lipopolysaccharide-binding protein.
This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag. The protein has a calculated MW of 38.6 kDa. The protein migrates as 45-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Specifications
AAH10507.1 | |
Biotinylated Human CD14, His,Avitag (CD4-H8228) is expressed from human 293 cells (HEK293). It contains AA Thr 20 - Met 344 (Accession # P08571-1). | |
-20°C | |
CD14 | |
Human | |
PBS, pH7.4 | |
HEK293 | |
MABSol™ Biotin Labeled Proteins |
38.6 kDa | |
Thr 20 - Met 344 | |
CD14 | |
Precision Avi | |
His Tag & Avi Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>95% as determined by SDS-PAGE. |