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Invitrogen™ BMI-1 Monoclonal Antibody (282CT3.7.6)
Mouse Monoclonal Antibody
Brand: Invitrogen™ MA537525
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Beskrivning
BMI-1 Monoclonal Antibody for Western Blot, ICC/IF
Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
Specifikationer
| BMI-1 | |
| Monoclonal | |
| Unconjugated | |
| BMI1 | |
| AW546694; B lymphoma Mo-MLV insertion region 1; B lymphoma Mo-MLV insertion region 1 homolog; Bmi1; Bmi-1; BMI1 polycomb ring finger oncogene; BMI1 polycomb ring finger proto-oncogene; BMI1 proto-oncogene, polycomb ring finger; FLVI2/BMI1; flvi-2/bmi-1; murine leukemia viral (bmi-1) oncogene homolog; Pcgf4; Pcgf4 antibody; Polycomb complex protein BMI-1; polycomb group protein Bmi1; polycomb group ring finger 4; polycomb group RING finger protein 4; RING finger protein 51; RNF51; RP11-573G6.1 | |
| Mouse | |
| Protein G | |
| RUO | |
| 648 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Western Blot, Immunocytochemistry | |
| 282CT3.7.6 | |
| PBS with 0.09% sodium azide; pH 7.4 | |
| P35226 | |
| BMI1 | |
| BMI1 recombinant protein. | |
| 400 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 κ |
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