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BMPR1B (ALK6) Recombinant Human Protein

BMPR1B (ALK6) Recombinant Human Protein

Brand:  Invitrogen PV6236

UNSPSC : 12352202

Additional Details : Weight : 0.01000kg

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Product Code. 15498893

  • 10180.00 SEK / 100µg


Estimated Shipment date
from Supplier 04-09-2017
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Disclaimers:

For Research Use Only. Not for use in diagnostic procedures.


Description

Description

BMPR1B (also known as ALK6) is a member of the transmembrane serine/threonine kinase that is the member of the bone morphogenetic protein (BMP) receptor, which is closely related to the activin receptors, ACVR1 and ACVR2. BMPR1B is mainly involved in the endochondral bone formation and embryogenesis. BMPR1B expressed in normal and cancerous prostate tissues and used in the endocrine therapy that given to the prostate cancer patients. BMPR1B receptor trafficking also play a significant role in FOP pathogenesis and used in human T-cell differentiation. Recombinant human BMPR1B (149-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. Recombinant human BMPR1B (149-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

  • Validated in LanthaScreen™ Kinase Binding Assay
  • Protocols available for simple use and optimized performance
  • Multiple pack sizes available for convenient use

    Related Product:
    LanthaScreen™ Eu Kinase Binding Assay
  • Specifications

    Specifications

    NP_001194.1
    Pharma and biopharma, protein assays and analysis, target and lead identification and validation
    BMPR1B (ALK6) Recombinant Human Protein
    >90% by SDS-PAGE
    –68 to –85°C
    1 Each
    BMPR1B (ALK6) Recombinant Human Protein
    Kinase assay
    BMPR1B (ALK6) Recombinant Human Protein
    Human
    0.1mg/mL
    66.7kDa
    7.5
    100μg
    For research use only. Not for use in diagnostic procedures
    ALK-6, ALK6, CDw293
    BMPR1B (ALK6) was pre-diluted in enzyme dilution buffer and assayed in 5mM MOPS (pH 7.2), 2.5mM β-glycerol-phosphate, 5mM MgCl2, 0.4mM EDTA, 1mM EGTA, 0.05mM DTT, with 50μM ATP, trace [33P]-γ-ATP and 200μg/mL TGFBR1 peptide substrate (KKKVLTQMGSPSIRCS(pS)VS) for 15 min.s at 30°C
    Amino acids 149-end
    19nmoles of phosphate transferred to TGFBR1 peptide substrate (KKKVLTQMGSPSIRCS(pS)VS) per minute per mg of total protein at 30°C
    GST Tag