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  5. STEMCELL Technologies BMS 493

STEMCELL Technologies BMS 493

Product Code. 17150302
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17140302 1 mg
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Product Code. 17150302 Supplier STEMCELL Technologies Supplier No. 73974

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Description

Retinoid pathway activator; Activates pan-retinoic acid receptor

  • BMS 493 is an inverse agonist of the pan-retinoic acid receptors (RARs)
  • RARs are ligand-dependent transcription factors that regulate gene networks that control cell growth, differentiation, survival, and death (Germain et al.) BMS 493 has been shown to increase nuclear receptor co-repressor (NCoR) interaction with RARs (Germain et al.; Rinkevich et al.)
  • Affects development of bronchial tubule formation in mice (Chazaud et al.)
  • Inhibits activation of immature dendritic cells (Geissmann et al.)
  • Inhibits differentiation of leukemic blasts (Kamashev et al.)

Specifications

CAS 215030-90-3
Synonym BMS 204493
Kvantitet 10 mg
Molekylformel C29H24O2
Renhet ≥98%
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