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Eurofins DiscoverX Bmx Protein, Active
Beskrivning
BMX (also called ETK, Bone marrow tyrosine kinase gene in chromosome X protein, Epithelial and endothelial tyrosine kinase) is one of the non-receptor tyrosine kinases, located intracellularly. It is a src homolog and contains an SH3 and SH2 domain upstream from the tyrosine kinase domain. Unlike other members of the BTK family kinases, which are mostly hemopoietic cell-specific, BMX is preferentially expressed in epithelial and endothelial cells of large arteries. Inhibitors of BMX may be useful in the treatment of atherosclerosis and cancer.
GenBank NM_001721
Specifikationer
Specifikationer
| Formulering | mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 150 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution. |
| Molekylvikt (g/mol) | 79 kDa |
| Kvantitet | 250 μg |
| Art | Human |
| Rekombinant | Recombinant |
| Protein Tag | N-terminal 6His |
| Uttryckssystem | Recombinant enzyme expressed in Sf21 insect cells |
| Proteinform | Full-length |
| Renhet eller kvalitetsklass | ≥63% |
| Protein | Bmx, active |
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