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Invitrogen™ BRSK2 Recombinant Human Protein

BRSK2 is a brain-selective serine/threonine kinase 2 that is mainly expressed in the brain, with weaker expression in testis and pancreas. Recombinant full-length human BRSK2 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

3605.00 SEK - 55100.00 SEK

Specifications

Host Species Human
Protein Tag GST Tag
Recombinant Yes
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Products 3
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15438923
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Invitrogen™
PV6260
100μg
12320.00 SEK
100µg
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Estimated Shipment: 11-02-2022
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15428923
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Invitrogen™
PV6259
10μg
3605.00 SEK
10µg
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Estimated Shipment: 11-02-2022
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15448923
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Invitrogen™
PV6261
1mg
55100.00 SEK
1mg
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»
Estimated Shipment: 11-02-2022
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Description

Description

BRSK2 expressed in insect cells specifically phosphorylates WEE1A, CDC25C and CDC25B in an in vitro assay. DNA damage induced by ultraviolet (UV) irradiation or methyl methane sulfonate, but not by ionizing radiation, enhanced endogenous BRSK2 kinase activity in a caffeine-sensitive manner and caused translocation of BRSK2 from the cytoplasm to the nucleus. Overexpression of BRSK2 induces G2/M arrest in HeLa cells while small interfering RNA against BRSK2 partly abrogated UV-induced G2/M arrest. Mammalian BRSK2 kinases are required for neuronal polarization.

  • Validated in LanthaScreen™ Kinase Binding Assay
  • Protocols available for simple use and optimized performance
  • Multiple pack sizes available for convenient use
Specifications

Specifications

Human
GST Tag
Yes
SDS
Product Certifications