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BX795, MedChemExpress

Produktkod. 16406737
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Kvantitet:
5 mg
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100 mg
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Förpackningsstorlek:
100mg
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Produktkod. 16406737

Brand: Medchem Express HY10514

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Description

MedChemExpress BX795 is a potent and selective inhibitor of PDK1, with an IC50 of 6 nM. BX795 is also a potent and relatively specific inhibitor of TBK1 and IKKɛ, with an IC50 of 6 and 41 nM, respectively. BX795 blocks phosphorylation of S6K1, Akt, PKCδ, and GSK3β, and has lower selectivity over PKA, PKC, c-Kit, GSK3β etc. BX795 modulates autophagy.

BX795 is a potent and selective inhibitor of PDK1, with an IC50 of 6 nM. BX795 is also a potent and relatively specific inhibitor of TBK1 and IKKɛ, with an IC50 of 6 and 41 nM, respectively. BX795 blocks phosphorylation of S6K1, Akt, PKCδ, and GSK3β, and has lower selectivity over PKA, PKC, c-Kit, GSK3β etc. BX795 modulates autophagy.

Specifications

Kemiskt namn eller material BX795
Fysisk form Solid
CAS 702675-74-9
Färg Light Gray
Kvantitet 5 mg
Anteckningar om renhetsgrad Research
Molekylformel C23H26IN7O2S
För användning med (applikation) Cancer-Kinase/protease
Löslighetsinformation DMSO : 33.33 mg/mL (56.35 mM; Need ultrasonic)
LEDER O=C(NCCCNC1=C(C=NC(NC2=CC=CC(NC(N3CCCC3)=O)=C2)=N1)I)C4=CC=CS4
Molekylvikt (g/mol) 591.47
Formel vikt 591.47
Procent renhet 98.93%
Kvalitet Research
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Research purposes only

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