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Invitrogen™ C5AR1 Biosimilar Recombinant Monoclonal Antibody
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Produktkod. 30284375
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Kvantitet:
1 mg
100 μg
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Produktkod. Kvantitet
30284375 100 μg
30282842 1 mg
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Produktkod. 30284375 Leverantör Invitrogen™ Leverantörsnummer MA558459

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Beskrivning

Recombinant Monoclonal Antibody

For reconstitution, add sterile, distilled water to achieve a final antibody concentration of 1 mg/mL. Gently shake to solubilize the protein completely. Do not vortex. Reconstituted products should be stored at -80 °. This antibody can also be cross referenced by the term G2_anti-C5aR.

CD88, also known as C5aR1, is a C5a Anaphylatoxin Receptor that mediates the effects of one of the most potent chemotactic agents known. C5AR1 has been implicated in asthma, and its expression has been reported in myeloid blood cells, brain, liver, lung, spleen, heart, kidney, and intestinal tract. CD88 is the receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. Functionally, CD88 stimulates chemotaxis, granule enzyme release and superoxide anion production. CD88 is also a component of the classical pathway of the complement cascade; it may be involved with tissue injury associated with ischemia or sepsis and it may be a component of the membrane attack complex. Diseases associated with CD88 include Mannose-Binding Lectin Deficiency and Systemic Lupus Erythematosus.
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Specifikationer

Antigen C5AR1 Biosimilar
Användningsområden ELISA, Flow Cytometry, Functional Assay, Surface Plasmon Resonance
Klassificering Recombinant Monoclonal
Koncentration 1 mg/mL
Konjugera Unconjugated
Formulering 25mM histidine with 8% sucrose, 0.01% Tween 80 and no preservative; pH 6.2
Värd art Human
Reningsmetod Protein A
Kvantitet 100 μg
Regulatorisk status RUO
Primär eller sekundär Primary
Målarter Human
Innehåll och lagring -20°C, Avoid Freeze/Thaw Cycles
Produkttyp Antibody
Form Lyophilized
Isotyp IgG4SP
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