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CADM1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 14335-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16822924

  • 3248.87 SEK / 150µL
Estimated Shipment: 30-11-2021

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Description

Description

Mediates homophilic cell-cell adhesion in a Ca (2+)-independent manner. Also mediates heterophilic cell-cell adhesion with CADM3 and PVRL3 in a Ca (2+)-independent manner. Acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. May contribute to the less invasive phenotypes of lepidic growth tumor cells. In mast cells, may mediate attachment to and promote communication with nerves. CADM1, together with MITF, is essential for development and survival of mast cells in vivo. May act as a synaptic cell adhesion molecule that drives synapse assembly. May be involved in neuronal migration, axon growth, pathfinding, and fasciculation on the axons of differentiating neurons. May play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa.
Specifications

Specifications

CADM1
0.16 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q6AYP5, Q8R5M8, Q9BY67
BL2, CADM1, cell adhesion molecule 1, IGSF4, IGSF4A, Necl 2, NECL2, Nectin like protein 2, RA175, sgIGSF, ST17, sTSLC 1, SYNCAM, synCAM1, TSLC 1, TSLC1
Rabbit
IgG
150 μL
-20°C
Primary
23705, 363058, 54725
Western Blot
Unconjugated
CADM1
Liquid
Cadm1
CADM1 Fusion Protein Ag5621
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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