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Calponin Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 24855-1-AP-20UL
Additional Details : Weight : 0.00010kg
Description
This antibody raised against the specific region of human CNN1, thus it does not cross-react with CNN2 or CNN3.
Calponin, a thin filament associated protein is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. Calponin is expressed in smooth muscle and tissues containing significant amounts of smooth muscle. Two isoforms of calponin exist whose molecular weights are 34kDa and 29kDa. Expression of the 29kDa form is primarily restricted to muscle of the urogenital tract. The expression of calponin has also been demonstrated in myoepithelial cells from benign and maligt breast lesions. It stains smooth muscle, myoepithelial cells, myofibroblasts, keratinocytes and nerve fibers. It identifies myoepithelial cells in breast lesions, and helps differentiate breast collagenous spherulosis (positive) from adenoid cystic carcinoma. Adenoid cystic carcinoma in salivary gland tumors is calponin positive.Specifications
Calponin | |
Polyclonal | |
Unconjugated | |
CNN1 | |
Basic calponin, Calponin, Calponin 1, Calponin H1, smooth muscle, CNN1, Sm Calp, SMCC | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
1264, 12797 | |
-20°C | |
Liquid |
Western Blot, Immunohistochemistry (Paraffin) | |
0.33 mg/mL | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
P51911, Q08091 | |
CNN1 | |
Calponin Fusion Protein Ag21384 | |
20 μL | |
Primary | |
Mouse, Human | |
Antibody | |
IgG |