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Calponin Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 24855-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16823355

  • 1236.20 SEK / 20µL
Estimated Shipment: 07-12-2021

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Description

Description

This antibody raised against the specific region of human CNN1, thus it does not cross-react with CNN2 or CNN3.

Calponin, a thin filament associated protein is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. Calponin is expressed in smooth muscle and tissues containing significant amounts of smooth muscle. Two isoforms of calponin exist whose molecular weights are 34kDa and 29kDa. Expression of the 29kDa form is primarily restricted to muscle of the urogenital tract. The expression of calponin has also been demonstrated in myoepithelial cells from benign and maligt breast lesions. It stains smooth muscle, myoepithelial cells, myofibroblasts, keratinocytes and nerve fibers. It identifies myoepithelial cells in breast lesions, and helps differentiate breast collagenous spherulosis (positive) from adenoid cystic carcinoma. Adenoid cystic carcinoma in salivary gland tumors is calponin positive.
Specifications

Specifications

Calponin
0.33 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P51911, Q08091
Basic calponin, Calponin, Calponin 1, Calponin H1, smooth muscle, CNN1, Sm Calp, SMCC
Rabbit
IgG
20 μL
-20°C
Primary
1264, 12797
Western Blot, Immunohistochemistry (Paraffin)
Unconjugated
CNN1
Liquid
CNN1
Calponin Fusion Protein Ag21384
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Mouse, Human
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