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CAMK2G (CaMKII gamma) Recombinant Human Protein

CAMK2G (CaMKII gamma) Recombinant Human Protein

Brand:  Invitrogen PV6270

Additional Details : Weight : 0.01000kg

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Product Code. 15478923

  • 45530.00 SEK / 1mg


Estimated Shipment date
from Supplier 01-11-2017
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Disclaimers:

For Research Use Only. Not for use in diagnostic procedures.


Description

Description

CAMK2G (CaMKII gamma) is a member of the CAMKII family which are ubiquitous serine/threonine protein kinases that have been implicated in diverse effects of hormones and neurotransmitters. CAMK2G has six alternatively spliced variants that encode six different isoforms. Some of these variants have been identified in human tumors. Transgenic mice expressing a partially calcium-independent mutant form of CAMKG showed 1.5- to 2-fold increase in the thymus of these mice, at least in part due to an increase in the life span of double-positive thymocytes. There was an increase in the number of T cells in the secondary lymphoid organs that had acquired an antigen-dependent memory phenotype. Recombinant human CAMK2G (c-terminal truncation) was expressed by baculovirus in Sf9 cells using an N-terminal GST tag.

  • Validated in LanthaScreen™ Kinase Binding Assay
  • Protocols available for simple use and optimized performance
  • Multiple pack sizes available for convenient use

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  • Specifications

    Specifications

    NP_751909.1
    Pharma and biopharma, protein assays and analysis, target and lead identification and validation
    CAMK2G (CaMKII gamma) Recombinant Human Protein
    1mg
    For research use only. Not for use in diagnostic procedures
    CAMKG, CAMK, CAMK-II, MGC26678
    CAMK2G (CaMKII gamma) was pre-diluted in enzyme dilution buffer and assayed in 5mM MOPS (pH 7.2), 2.5mM β-glycerol-phosphate, 5mM MgCl2, 0.4mM EDTA, 1mM EGTA, 0.05mM DTT, with 50μM ATP, trace [33P]-γ-ATP and 200μg/mL Autocamtide-2 peptide substrate (KKALRRQETVDAL-amide) for 15 min.s at 30°C
    Amino acids c-terminus, contains S36P SNP
    285nmoles of phosphate transferred to Autocamtide-2 peptide substrate (KKALRRQETVDAL-amide) per minute per mg of total protein at 30°C
    GST Tag
    0.1mg/mL
    60.9kDa
    >75% by SDS-PAGE
    –68 to –85°C
    1 Each
    CAMK2G (CaMKII gamma) Recombinant Human Protein
    Kinase assay
    CAMK2G (CaMKII gamma) Recombinant Human Protein
    Human