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Invitrogen™ Cardiac Troponin T Monoclonal Antibody (13-11)
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Produktkod. 11314753
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Kvantitet:
200 μL
Förpackningsstorlek:
500µL
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Produktkod. Kvantitet unitSize
11314753 200 μL 500µL
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Produktkod. 11314753 Leverantör Invitrogen™ Leverantörsnummer MA512960

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3401.00 SEK valid until 2026-04-10
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Beskrivning

Mouse Monoclonal Antibody

MA5-12960 targets Troponin T Cardiac Isoform in IF/ICC, IHC (P), and IM applications and shows reactivity with Avian, Canine, Chicken, Fish, Guinea Pig, Human, mouse, Porcine, Rabbit, and Rat samples. The MA5-12960 immunogen is purified rabbit cardiac troponin T isoform (TnT4R).

Cardiac Troponin T is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Cardiac Troponin T is important in proper muscle function and myofibril formation. In the human heart, four cTnT isoforms are expressed in a developmentally regulated manner. Cardiac Troponin T expression in the human heart is affected by heart failure. Mutations within the Cardiac Troponin T protein have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for the Cardiac Troponin T gene undergo alternative splicing that results in many tissue-specific isoforms.
TRUSTED_SUSTAINABILITY

Specifikationer

Antigen Cardiac Troponin T
Användningsområden Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Klassificering Monoclonal
Klona 13-11
Koncentration 0.5 mg/mL
Konjugera Unconjugated
Formulering PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gen TNNT2
Genaccessionsnr. P02642, P09741, P45379, P50752, P50753
Gene Alias alternatively spliced; cardiac muscle troponin T; cardiac TnT; cardiac troponin 2; cardiac troponin 2 adult #1 isoform; cardiac troponin 2 adult #2 isoform; cardiac troponin 2 embryonic #1 isoform; cardiac troponin 2 embryonic #2 isoform; cardiac troponin 2, exclusion exon 6 #1 isoform; cardiac troponin 2, exclusion exon 6 #2 isoform; cardiac troponin T; cardiac troponin T form I; cardiac troponin T isoform 1; cardiac troponin T isoform 2; cardiac troponin T isoform I; cardiac troponin T2; cardiomyopathy, dilated 1D (autosomal dominant); cardiomyopathy, hypertrophic 2; CMD1D; CMH2; CMPD2; cTnT; Ctt; CTTG; LVNC6; MGC3889; RATCTTG; RCM3; TNNT2; Tnnt3; Tnt; TnTc; troponin T; Troponin T cardiac; troponin T cardiac isoform; troponin T isoform 1; troponin T isoform 2; troponin T splicing mutant isoform 1; troponin T splicing mutant isoform 2; troponin T type 2 (cardiac); troponin T, cardiac muscle; Troponin T, cardiac muscle isoforms; Troponin T2; troponin T2, cardiac; troponin T2, cardiac type; truncated cardiac troponin T
Gensymboler TNNT2
Värd art Mouse
Immunogen Purified rabbit cardiac troponin T isoform (TnT4R).
Reningsmetod Affinity chromatography
Kvantitet 200 μL
Regulatorisk status RUO
Primär eller sekundär Primary
Gen-ID (Entrez) 100009428, 100379561, 100622450, 21956, 24837, 396433, 403532, 7139
Målarter Avian, Canine, Chicken, Fish, Guinea Pig, Human, Mouse, Pig, Rabbit, Rat
Innehåll och lagring 4°C
Produkttyp Antibody
Form Liquid
Isotyp IgG1
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