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Invitrogen™ CAS Monoclonal Antibody (P729)
Mouse Monoclonal Antibody
Brand: Invitrogen™ MA518303
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Beskrivning
Recommended positive controls: 293T, A431, HeLa, HepG2, Neuro2A, GL261, C8D30, NIH-3T3, BCL-1, Raw264.7, C2C12, PC-12, Rat2. Predicted reactivity: Mouse (99%), Rat (100%), Zebrafish (95%), Xenopus laevis (97%), Pig (100%), Rhesus Monkey (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation.
Specifikationer
| CAS | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with no preservative | |
| P55060, Q9ERK4 | |
| CSE1L | |
| Recombinant protein encompassing a sequence within the center region of human CSE1L. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG2a |
| Western Blot, Immunocytochemistry | |
| P729 | |
| Unconjugated | |
| CSE1L | |
| 2610100P18Rik; AA407533; Capts; CAS; Cellular apoptosis susceptibility protein; chromosome segregation 1 like; chromosome segregation 1-like (S. cerevisiae); chromosome segregation 1-like protein; CSE1; CSE1 chromosome segregation 1 like; CSE1 chromosome segregation 1-like; CSE1 chromosome segregation 1-like (yeast); CSE1L; Exp2; exportin-2; Importin-alpha re-exporter; MGC117283; MGC130036; MGC130037; XPO2 | |
| Mouse | |
| Protein G | |
| RUO | |
| 110750, 1434, 362273 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
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