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Casein Kinase 1 epsilon Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 11230-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16878163

  • 1236.20 SEK / 20µL
Estimated Shipment: 07-12-2021

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Description

Description

Casein kinases are a group of ubiquitous Ser/Thr kinases that phosphorylate key regulatory proteins involved in the control of cell differentiation, proliferation, chromosome segregation, circadian rhythms, and metabolic pathways. CK1 family members share a highly conserved kinase domain but differ in their variable N-and C-terminal domains. Mammals have seven family members: alpha, beta, gamma1, gamma2, gamma3, delta and epsilon. They all share at least 50% amino acid identity within the protein kinase catalytic domain. CK1 isoforms exclusively use ATP as phosphate donor and are generally co-factor independent. Casein kinase I epsilon is a Wnt-regulated kinase, and regulated phosphorylation of Dvl allows fine tuning of the Wnt-b-catenin signaling pathway. CKIe positively regulates Akt possibly by inhibiting PP2A. CKIe play an important role in neurodegenerative diseases.
Specifications

Specifications

Casein Kinase 1 epsilon
0.4 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P49674, Q9JMK2
Casein Kinase 1 epsilon, casein kinase 1, epsilon, CKI epsilon, CKIe, CSNK1E, HCKIE
Rabbit
IgG
20 μL
-20°C
Primary
1454, 27373, 58822
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
CSNK1E
Liquid
CSNK1E
Casein Kinase 1 epsilon Fusion Protein Ag1742
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Rat, Mouse
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