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Caspase 11 Rat anti-Mouse, Clone: 17D9, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-9935-82

Additional Details : Weight : 0.01000kg

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Product Code. 15228257

  • 2345.00 SEK / 100µg


Estimated Shipment
07-12-2020
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Description

Description

This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.
Specifications

Specifications

Caspase 11
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P70343
ICE(rel)II, ICEREL-II, ICH-2, Mih1/TX, TX
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Western Blot
17D9
Unconjugated
Casp4
Liquid
Casp4
IgG2a
100 μg
4° C
Primary
12363
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SDS
Documents

For Research Use Only.