Caspase 11 Rat anti-Mouse, Clone: 17D9, eBioscience™
Rat Monoclonal Antibody
Brand: Affymetrix eBioscience 14-9935-82
Additional Details : Weight : 0.01000kg
DescriptionThis gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.
|PBS with 0.09% sodium azide; pH 7.2|
|ICE(rel)II, ICEREL-II, ICH-2, Mih1/TX, TX|
For Research Use Only.