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Invitrogen™ Caspase 3 Monoclonal Antibody (4-1-18)
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Produktkod. 10049202
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Kvantitet:
100 μg
Förpackningsstorlek:
Varje
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10049202 100 μg Varje
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For Research Use Only. All usage must comply with product instructions.
Produktkod. 10049202 Leverantör Invitrogen™ Leverantörsnummer 351600Z

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For Research Use Only. All usage must comply with product instructions.

Beskrivning

Mouse Monoclonal Antibody

Caspase 3 Monoclonal Antibody for Western Blot, IHC

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.
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Specifikationer

Antigen Caspase 3
Användningsområden Immunohistochemistry, Western Blot
Klassificering Monoclonal
Klona 4-1-18
Koncentration 0.5 mg/mL
Konjugera Unconjugated
Formulering PBS with 0.1% sodium azide; pH 7.4
Gen CASP3
Genaccessionsnr. P42574
Gene Alias A830040C14Rik; AC-3; Apopain; Apopain precursor; Casp3; CASP-3; caspase 3; Caspase 3 apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis related cysteine protease; Caspase 3, apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis-related cysteine peptidase; caspase 3, apoptosis-related cysteine protease; Caspase3; caspase-3; Caspase-3 subunit p12; Caspase-3 subunit p17; Caspase-3-like protein; CC3; Cpp32; CPP-32; CPP32B; CPP32beta; cysteine protease CPP32; cysteine protease; CPP32; apopain; ICE3; IRP; LICE; mldy; PARP cleavage protease; procaspase3; protein Yama; SCA-1; SREBP cleavage activity 1; Yama; yama protein
Gensymboler CASP3
Värd art Mouse
Immunogen Full length, recombinant human caspase 3 protein.
Reningsmetod Protein A
Kvantitet 100 μg
Regulatorisk status RUO
Primär eller sekundär Primary
Gen-ID (Entrez) 836
Målarter Human
Innehåll och lagring Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Produkttyp Antibody
Form Liquid
Isotyp IgG2a
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