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Thermo Scientific™ Lab Vision™ β-Catenin Rabbit Monoclonal Antibody

Ensure accurate and reproducible results in immunohistochemistry applications with this antibody, part of a comprehensive antibody portfolio.

1694.72 SEK - 7784.88 SEK

Specifications

Antigen Catenin, beta
Clone E247
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Conjugate Unconjugated
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Products 4
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
12693597 View Documents Thermo Scientific™
RM-2101-RQ
12mL 5355.92 SEK
12mL View alternative products
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Estimated Shipment date
from Supplier 13-09-2019
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12603607 View Documents Thermo Scientific™
RM-2101-S0
100μL 1694.72 SEK
100µL View alternative products
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Estimated Shipment date
from Supplier 13-09-2019
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12673597 View Documents Thermo Scientific™
RM-2101-R7
7mL 4183.73 SEK
7mL View alternative products
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Estimated Shipment date
from Supplier 13-09-2019
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12683597 View Documents Thermo Scientific™
RM-2101-S
1mL 7784.88 SEK
1mL View alternative products
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Estimated Shipment date
from Supplier 13-09-2019
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Description

Description

The catenins (α, β and γ) are ubiquitously expressed cytoplasmic proteins associated with E-cadherin at cellular junctions. β-catenin also binds to N-cadherin and co-immunoprecipitates with APC. Cadherin/catenin complexes are linked to the cytoskeleton via a direct association between α-actinin and α-catenin. Increased tyrosine phosphorylation can disrupt catenin-cadherin complexes, influencing cellular adhesion. Mutations in the catenin gene, CTNNB1, have been implicated in its accumulation and various forms of carcinomas.

Host Species: Rabbit

Clone: E247

Species Reactivity: Human. Others not known.

Immunogen: A synthetic peptide derived from near the N-terminus of human β-catenin

Molecular Weight: 92 kDa

Positive Control: Breast CA

Cellular Localization: Cell Membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)

Specifications

Specifications

Catenin, beta
Immunohistochemistry (Paraffin)
Unconjugated
IVD
Primary
E247
Monoclonal
Rabbit
Cancer and Tumor Biology
A synthetic peptide derived from near the N-terminus of human beta-catenin