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Invitrogen™ Cathelicidin Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5120383
3817.50 SEK valid until 2025-12-19
BÄSTA PRIS på kampanj! Använd kampanjkod: "24110" för att få ditt kampanjpris.
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Beskrivning
Positive test controls include: MCF7, A-549, PC-3, SP2/0, mouse testis, mouse spleen. The target is usually found in the following locations: Secreted. Immunogen sequence: NKRFALLGDF FRKSKEKIGK EFKRIVQRIK DFLRNLVPR.
Cathelicidin is an epithelial-derived antimicrobial protein found in specific granules of polymorphonuclear leukocytes of bone marrow, testis and neutrophils. Cathelicidins are one family of antimicrobial peptides characterized by conserved pro-peptide sequences that have been identified in epithelial tissues and some myeloid cells of humans and animals. LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells. The presence of these molecules is essential for defense against invasive bacterial infection in skin. Besides their direct antimicrobial function, Cathelicidins have multiple roles in mediating innate and adaptive immunity, such as endotoxin neutralizing, angiogenesis, wound healing and promoting neutrophil chemotaxis and mast cell recruitment. Cathelicidin antimicrobial peptides qualify as prototypes of innovative drugs that may be used to treat infection and/or modulate the immune response.
Specifikationer
| Cathelicidin | |
| Polyclonal | |
| Unconjugated | |
| CAMP | |
| 18 kDa cationic antimicrobial protein; Antibacterial peptide FALL-39; Antibacterial peptide LL-37; Camp; CAP18; CAP-18; Cathelicidin antimicrobial peptide; cathelin-like protein; Cathelin-related antimicrobial peptide; CLP; Cnlp; CRAMP; FALL39; FALL-39; FALL-39 peptide antibiotic; hCAP18; hCAP-18; HSD26; LL37; MCLP | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 316010, 820 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 2.7 mg/mL | |
| PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3 | |
| P49913 | |
| CAMP | |
| Recombinant fusion protein containing a sequence corresponding to amino acids 132-170 of human CAMP (NP_004336.3). | |
| 100 μL | |
| Primary | |
| Human, Rat | |
| Antibody | |
| IgG |
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