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Cathepsin A Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 15020-1-AP-20UL
Additional Details : Weight : 0.00010kg
Description
The cathepsin family of proteolytic enzymes include several diverse classes of proteases. Cathepsins B, L, H, K, S and O comprise the cysteine protease class. Cathepsins D and E comprise the aspartyle protease class. The serine protease class includes cathepsin G. Cathepsins function in cellular metabolism and participate in peptide biosynthesis and protein degradation. Cathepsin A, a serine carboxypeptidase, exists in a high molecular weight lysosomal complex with b-galactosidase (b-gal) and a-neuraminidase (Neu1). Cathepsin A functions to protect b-gal and Neu1 from intralysosomal proteolysis. Deficiencies in cathepsin A lead to deficiencies in b-gal and Neu1. The gene encoding human cathepsin A maps to chromosome 20q13.12. Mutations in this gene cause glactosialidosis, a lysosomal storage disorder resulting from the b-gal and Neu1 deficiencies.Specifications
Cathepsin A | |
Polyclonal | |
Unconjugated | |
CTSA | |
Carboxypeptidase C, Carboxypeptidase L, Cathepsin A, CTSA, GLB2, GSL, Lysosomal protective protein, NGBE, PPCA, PPGB, Protective protein cathepsin A | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
19025, 296370, 5476 | |
-20°C | |
Liquid |
Western Blot | |
0.46 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
P10619, P16675 | |
Ctsa | |
Cathepsin A Fusion Protein Ag7073 | |
20 μL | |
Primary | |
Mouse, Human, Rat | |
Antibody | |
IgG |