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Cathepsin F Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 11055-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16827873

  • 1236.20 SEK / 20µL
Estimated Shipment: 08-12-2021

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Description

Description

Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. Cathepsins generally contain a signal sequence, followed by a propeptide and then a catalytically active mature region. The very long (251 amino acid residues) proregion of the cathepsin F precursor contains a C-terminal domain similar to the pro-segment of cathepsin L-like enzymes, a 50-residue flexible linker peptide, and an N-terminal domain predicted to adopt a cystatin-like fold. The cathepsin F proregion is unique within the papain family cysteine proteases in that it contains this additional N-terminal segment predicted to share structural similarities with cysteine protease inhibitors of the cystatin superfamily. This cystatin-like domain contains some of the elements known to be important for inhibitory activity. CTSF encodes a predicted protein of 484 amino acids which contains a 19 residue signal peptide. Cathepsin F contains five potential N-glycosylation sites, and it may be targeted to the endosomal/lysosomal compartment via the mannose 6-phosphate receptor pathway. The cathepsin F gene is ubiquitously expressed, and it maps to chromosome 11q13, close to the gene encoding cathepsin W.
Specifications

Specifications

Cathepsin F
0.25 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q9R013, Q9UBX1
Cathepsin F, CATSF, CTSF
Rabbit
IgG
20 μL
-20°C
Primary
361704, 56464, 8722
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
CTSF
Liquid
Ctsf
Cathepsin F Fusion Protein Ag1521
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Rat, Mouse
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