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CCBL1/KAT1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 12156-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16879693

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Description

Description

Kynurenine aminotransferases KAT I, KAT II, and KAT III belong to the class-I pyridoxal-phosphate-dependent aminotransferase family. KAT I is a cytoplasmic protein involved in glutamine catabolism. KAT I functions in the catalysis of the transamination of L-kinurenine to form kynurenic acid, a neuroprotective and anticonvulsant metabolite of tryptophan. Kynurenic acid is involved in synaptic transmission and has been implicated in a number of neurological disorders including schizophrenia and Huntington′s disease. KAT I also functions in the metabolism of cysteine conjugates in some halogenated alkenes and alkanes to form reactive metabolites. KAT I has three isoforms. Isoform 1is the full length protein, isoform 2 lacks amino acids 68-117 and isoform 3 lacks amino acids 251-422. Based on sequence similarity, KAT I is thought to function as a homodimer.
Specifications

Specifications

CCBL1/KAT1
Polyclonal
Unconjugated
KYAT1
CCBL1, Glutamine transaminase K, GTK, KAT1, KATI, Kynurenine aminotransferase I
Rabbit
Antigen Affinity Chromatography
RUO
311844, 70266, 883
-20°C
Liquid
Immunocytochemistry, Immunofluorescence, Western Blot
0.23 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q08415, Q16773, Q8BTY1
Kyat1
CCBL1/KAT1 Fusion Protein Ag2828
20 μL
Primary
Human, Rat, Mouse
Antibody
IgG
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