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CCM2 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 26270-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16824785

  • 1236.20 SEK / 20µL
Estimated Shipment: 30-11-2021

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Description

Description

This gene encodes a scaffold protein that functions in the stress-activated p38 Mitogen-activated protein kinase (MAPK) signaling cascade. The protein interacts with SMAD specific E3 ubiquitin protein ligase 1 (also known as SMURF1) via a phosphotyrosine binding domain to promote RhoA degradation. The protein is required for normal cytoskeletal structure, cell-cell interactions, and lumen formation in endothelial cells. Mutations in this gene result in cerebral cavernous malformations. Multiple transcript variants encoding different isoforms have been found for this gene.
Specifications

Specifications

CCM2
0.24 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q9BSQ5
C7orf22, CCM2, Malcavernin, OSM, PP10187
Rabbit
IgG
20 μL
-20°C
Primary
83605
Immunocytochemistry, Immunofluorescence, Western Blot, Immunohistochemistry (Paraffin)
Unconjugated
CCM2
Liquid
CCM2
CCM2 Fusion Protein Ag24233
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
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