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CCR2a Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 16153-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16825684

  • 3313.85 SEK / 150µL
Estimated Shipment: 07-12-2021

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Description

Description

This antibody 16153-1-AP is raised against the peptide of 344-358 amino acids of CCR2a. It is specific to CCR2a.

CCR2, a chemokine receptor, is a regulator of monocyte/macrophage trafficking and is upregulated in response to inflammation. Resistance to HIV-1 infection or delayed progression to AIDS may be linked to CCR2 polymorphisms. The ligand for CCR2 is monocyte chemoattractant protein (MCP-1), a chemokine produced by endothelial cells, smooth muscle cells, and macrophages. Activation of monocytes by MCP-1 may mediate the monocytic infiltration of tissues in atherosclerosis and other inflammatory disorders including rheumatoid arthritis, alveolitis, and tumor infiltration. Two isoforms are produced by alternative splicing. CCR2 has been reported to be expressed in a wide variety of tissues, including blood, brain, heart, kidney, liver, lung, ovary, pancreas, spinal cord, spleen, thymus, and vessel. Increased expression of CCR2 has been documented in CD3+ lymphocytes in rheumatoid arthritis. ESTs have been isolated from liver/spleen and prostate libraries.
Specifications

Specifications

CCR2a
0.37 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P41597
C C chemokine receptor type 2, C C CKR 2, CC CKR 2, CCR 2, CCR2, CCR2a, CCR2b, CD192, CKR2, CKR2A, CKR2B, CMKBR2, MCP 1 R
Rabbit
IgG
150 μL
-20°C
Primary
729230
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
CCR2
Liquid
CCR2
Peptide
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
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