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CCR7 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 55425-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16826885

  • 4721.67 SEK / 150µL
Estimated Shipment: 03-04-2024
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Description

Description

CCR7 is a member of the G protein coupled receptor family, which is a subfamily of chemokines. CCR7 was identified to be induced by the Epstein Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. CCR7 has been reported to be expressed in blood, bone marrow, lymph node, and intestine. CCR7 is particularly expressed in lymphoid tissues and in activated B and T lymphocytes and has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. ESTs have been isolated from blood, embryo, lymph node, and thymus libraries. Receptors for the C - C chemokine family include CCR 1, CCR 2A, CCR 3, CCR 4, CCR 5 and the Duffy blood group antigen. The C-C receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation.
Specifications

Specifications

CCR7
Polyclonal
Unconjugated
CCR7
BLR2, C C chemokine receptor type 7, C C CKR 7, CC CKR 7, CCR 7, CCR7, CD197, CDw197, CMKBR7, EBI1, EVI1, MIP 3 beta receptor
Rabbit
Antigen Affinity Chromatography
RUO
1236
-20°C
Liquid
Flow Cytometry, Immunohistochemistry (Paraffin)
0.73 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P32248
CCR7
Peptide
150 μL
Primary
Human
Antibody
IgG
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