CD100 (SEMA4D) Mouse anti-Human, Alexa Fluor® 488, Clone: eBio133-1C6 (133-1C6), eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 53-1009-41
Additional Details : Weight : 0.23750kg
DescriptionSemaphorins are neuronal chemorepellants that direct pioneering neurons during nervous system development. CD100 (also known as semaphorin 4d), a 150 kDa homodimer, is a novel semaphorin that induces B cells to aggregate and improves their viability in vitro. CD100 modifies CD40-CD40L B cell signaling by augmenting B cell aggregation and survival and down regulating CD23 expression. CD72 is a lymphocyte receptor for the class IV semaphorin CD100, which is involved in regulating B cell signaling. CD100 is expressed on resting and PHA stimulated T cells. The protein is weakly expressed on NK cells, EBV transformed B cells, monocytes and tumor/peripheral blood T cell lines, and at higher density on activated T cells and B cells.
|PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2|
|A8; BB18; GR3; Leukocyte activation antigen CD100; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, 4D|
|Alexa Fluor® 488|
|4° C, store in dark, DO NOT FREEZE!|
For Research Use Only.