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CD100 (SEMA4D) Mouse anti-Human, Clone: eBio133-1C6 (133-1C6), eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-1009-80

Additional Details : Weight : 0.01000kg

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Product Code. 15217137

  • 1088.00 SEK / 25µg


Estimated Shipment
05-01-2021
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Description

Description

Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered. Semaphorins are neuronal chemorepellants that direct pioneering neurons during nervous system development. CD100 (also known as semaphorin 4d), a 150 kDa homodimer, is a novel semaphorin that induces B cells to aggregate and improves their viability in vitro. CD100 modifies CD40-CD40L B cell signaling by augmenting B cell aggregation and survival and down regulating CD23 expression. CD72 is a lymphocyte receptor for the class IV semaphorin CD100, which is involved in regulating B cell signaling. CD100 is expressed on resting and PHA stimulated T cells. The protein is weakly expressed on NK cells, EBV transformed B cells, monocytes and tumor/peripheral blood T cell lines, and at higher density on activated T cells and B cells.
Specifications

Specifications

CD100 (SEMA4D)
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
Q92854
A8; BB18; GR3; Leukocyte activation antigen CD100; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, 4D
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
ELISA, Flow Cytometry, Immunoprecipitation
eBio133-1C6 (133-1C6)
Unconjugated
SEMA4D
Liquid
SEMA4D
IgM
25 μg
4° C
Primary
10507
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For Research Use Only.