CD104 (Integrin beta 4) Rat anti-Human, Clone: 439-9B, eBioscience™
Rat Monoclonal Antibody
Brand: Affymetrix eBioscience 14-1049-82
Additional Details : Weight : 0.01000kg
DescriptionAggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered. Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
|CD104 (Integrin beta 4)|
|PBS with 0.09% sodium azide; pH 7.2|
|CD104 antigen, GP150, integrin beta-4, integrin beta-4 subunit, ITGB4|
|Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot|
For Research Use Only.