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CD105 (Endoglin) Monoclonal Antibody (MJ7/18), eBioscience™, Invitrogen™

Rat Monoclonal Antibody

658.00 SEK - 2830.00 SEK

Specifications

Antigen CD105 (Endoglin)
Clone MJ7/18
Concentration 0.5 mg/mL
Applications Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Classification Monoclonal
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Products 3
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15297147
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Affymetrix eBioscience
14-1051-82
100 μg
1112.00 SEK
100µg
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15207157
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Affymetrix eBioscience
14-1051-85
500 μg
2830.00 SEK
500µg
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Estimated Shipment: 07-05-2024
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15287147
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Affymetrix eBioscience
14-1051-81
50 μg This item is currently unavailable or has been discontinued.
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Description

Description

Description: The MJ7/18 monoclonal antibody reacts with the mouse CD105 molecule, also known as Endoglin. This 90 kDa disulfide-linked homodimer is expressed by vascular endothelial cells. It is suggested that CD105 functions in adhesion and embryonic angiogenesis. Applications Reported: The MJ7/18 antibody has been reported for use in flow cytometric analysis, immunoprecipitation, immunoblotting (WB), and immunohistochemical staining of frozen tissue sections. Applications Tested: The MJ7/18 antibody has been tested by flow cytometric analysis of bEnd.3 cells or mouse splenocytes. This can be used at less than or equal to 0.5 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered.

CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.
Specifications

Specifications

CD105 (Endoglin)
0.5 mg/mL
Monoclonal
Liquid
RUO
PBS with 0.09% sodium azide; pH 7.2
AI528660; AI662476; CD105; CD105 antigen; cell surface MJ7/18 antigen; Edg; END; Endo; Endoglin; endoglin (Osler-Rendu-Weber syndrome 1); Eng; HHT1; ORW; ORW1; S-endoglin; transmembrane glycoprotein
ENG
Primary
4° C
ENG
MJ7/18
Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Unconjugated
Rat
Mouse
Q63961
13805
IgG2a κ
Affinity chromatography
Antibody
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