Learn More
CD105 Monoclonal Antibody (SN6), PE, Invitrogen™
Mouse Monoclonal Antibody
Brand: Invitrogen MA180944
Additional Details : Weight : 0.01000kg
Description
Reconstitute with 1 mL of distilled water. After reconstitution, store product undiluted at 4oC in the dark. For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL. Mouse anti Human CD105 antibody, clone SN6 recognizes the human endoglin, also known as CD105. CD105 is a glycoprotein homodimer of approximately 95 kDa subunits expressed by endothelial cells, activated monocytes and some leukemia cells.
CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.Specifications
CD105 | |
Monoclonal | |
Conc. Not Determined | |
PBS with 1% BSA, 5% sucrose and 0.09% sodium azide; pH 7.4 | |
P17813 | |
ENG | |
Cell membrane antigens from fresh leukemia cells. | |
100 Tests | |
Primary | |
Equine, Human, Non-human Primate | |
Antibody | |
IgG1 |
Flow Cytometry | |
SN6 | |
PE | |
ENG | |
AI528660; AI662476; CD105; CD105 antigen; cell surface MJ7/18 antigen; Edg; END; Endo; Endoglin; endoglin (Osler-Rendu-Weber syndrome 1); Eng; HHT1; ORW; ORW1; S-endoglin; transmembrane glycoprotein | |
Mouse | |
Protein G | |
RUO | |
100070421, 2022 | |
4° C, store in dark, DO NOT FREEZE! | |
Lyophilized |