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CD120a (TNF Receptor I) Armenian Hamster anti-Mouse, Functional Grade, Clone: 55R-170, eBioscience™

Armenian Hamster Monoclonal Antibody

1086.00 SEK - 3000.00 SEK

Specifications

Antigen CD120a (TNF Receptor I)
Clone 55R-170
Target Species Mouse
Conjugate Functional Grade
Isotype IgG
View More Specs

Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15218547 View Documents Affymetrix eBioscience
16-1202-81
50 μg 1086.00 SEK
50µg View alternative products
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Estimated Shipment date
from Supplier 20-05-2020
Add to basket
 
15228547 View Documents Affymetrix eBioscience
16-1202-85
500 μg 3000.00 SEK
500µg View alternative products
Save Up to 
»
Estimated Shipment date
from Supplier 20-05-2020
Add to basket
 
Description

Description

Endotoxin Level: Less than 0.001 ng/μg antibody, as determined by LAL assay. Aggregation: Less than 10%, as determined by HPLC. TNFR1 (Tumor necrosis factor receptor 1) belongs to the tumor necrosis factor superfamily, and is one of the major TNF-alpha receptors. TNFR1 plays an important role in mediating, in cytokine mediated signaling, positive regulation of the NF-Kb pathway, positive regulation of angiogenesis, and negative regulation of gene expression. The extracellular domain of TNFR1 is also released into the circulatory system as soluble TNFR1 (sTNFR1). In humans, the TNFR1 gene is located on chromosome 12. Anti-apoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with TNFR1, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of TNFR1 were found to be associated with the autosomal domit periodic fever syndrome, and the impaired receptor clearance is thought to be a mechanism of the disease.
Specifications

Specifications

CD120a (TNF Receptor I)
Mouse
IgG
Monoclonal
Liquid
Antibody
4° C
55R-170
Functional Grade
Functional Assay, Neutralization
Primary
Monoclonal
PBS with no preservative; pH 7.2
RUO

For Research Use Only.