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CD122/IL2RB Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 13602-1-AP-20UL
Additional Details : Weight : 0.00010kg
Description
CD122 (Interleukin 2 receptor) is involved in T cell-mediated immune responses, primarily expressed in the hematopoietic system and is present in 3 forms. The low affinity form of CD122 is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from CD122. The protein encoded by the CD122 gene represents the beta subunit and is a type I membrane protein. Diseases associate with CD122 protein dysfunction include oligoarticular juvenile idiopathic arthritis and rheumatoid factor negative juvenile idiopathic arthritis.Specifications
CD122/IL2RB | |
Polyclonal | |
Unconjugated | |
IL2RB | |
CD122, IL 2 receptor subunit beta, IL 2R subunit beta, IL 2RB, IL2RB, interleukin 2 receptor, beta, P70 75, p75 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
16185, 3560 | |
-20°C | |
Liquid |
Western Blot, Immunohistochemistry (Paraffin) | |
0.15 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
P14784, P16297 | |
IL2RB | |
CD122/IL2RB Fusion Protein Ag3929 | |
20 μL | |
Primary | |
Mouse, Human | |
Antibody | |
IgG |