GP130 Mouse anti-Human, Biotin, Clone: AN-G30, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 13-1308-82
Additional Details : Weight : 0.25000kg
DescriptionThe protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described.
|PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2|
|CD130; CD130 antigen; gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form; gp130, oncostatin M receptor; GP130-RAPS; IL-6 receptor subunit beta; IL-6R subunit beta; IL6R-beta; IL6ST; interleukin receptor beta chain; membrane glycoprotein 130; membrane glycoprotein gp130; oncostatin-M receptor subunit alpha|
|Flow Cytometry, Immunoprecipitation, Western Blot|
|4° C, store in dark, DO NOT FREEZE!|
For Research Use Only.