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CD137 (4-1BB) Monoclonal Antibody (17B5), eFluor™ 450, eBioscience™, Invitrogen™

Syrian Hamster Monoclonal Antibody

934.00 SEK - 2840.00 SEK

Specifications

Antigen CD137 (4-1BB)
Clone 17B5
Concentration 0.2 mg/mL
Applications Flow Cytometry
Classification Monoclonal
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15589716
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Affymetrix eBioscience
48-1371-82
100 μg
2840.00 SEK
100µg
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15579716
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Affymetrix eBioscience
48-1371-80
25 μg This item is currently unavailable or has been discontinued.
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Description

Description

Description: The 17B5 monoclonal antibody reacts with mouse CD137, also known as 4-1BB, a member of the TNFR superfamily. CD137 is expressed as monomers, dimers, and tetramers on the surface of activated T cells around day 4-6 after activation through the TCR complex. Interaction of CD137 with its ligand, 4-1BBL, is reported to deliver a costimulatory signal important in the T-APC interaction. Recent data suggests CD317 is expressed on Tregs and may play a role in their proliferation. The monoclonal antibody 17B5 has strong antagonistic effect in in vitro functional assays. Applications Reported: This 17B5 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 17B5 antibody has been tested by flow cytometric analysis of stimulated mouse splenocytes. This can be used at less than or equal to 0.5 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. eFluor™ 450 is an alternative to Pacific Blue™. eFluor™ 450 emits at 445 nm and is excited with the Violet laser (405 nm). Please make sure that your instrument is capable of detecting this fluorochome. Excitation: 405 nm; Emission: 445 nm; Laser: Violet Laser.

CD137 (4-1BB) Monoclonal antibody specifically detects CD137 (4-1BB) in Mouse samples. It is validated for Flow Cytometry.
Specifications

Specifications

CD137 (4-1BB)
0.2 mg/mL
Monoclonal
Liquid
RUO
P20334
IgG
Affinity chromatography
Antibody
17B5
Flow Cytometry
eFluor 450
Syrian Hamster
Mouse
21942
Primary
4° C, store in dark, DO NOT FREEZE!
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